Commissariat à l'Energie Atomique et aux Energies Alternatives

(CEA)

The “infectious diseases models for innovative therapies infrastructure” (IDMIT; www.idmitcenter.fr) department of CEA is also a joint research unit of Université Paris-Saclay, Inserm and CEA, grouping scientists of diverse expertise (physicians, preclinical experts, biochemists, immunologists, microbiologists, physicists and bio-physicists) to favor integrated research programs from basic biology to preclinical and clinical studies in the fields of human infectious disease and immunology. The unit is implemented in two sites with highly specialized labs and facilities, for preclinical research at Fontenay-aux-Roses CEA research campus and for clinical research at University Paris Saclay school of medicine in Bicêtre hospital. The department coordinates the IDMIT national infrastructure specialized in pre-clinical studies related to infectious diseases. With a primary focus on developing advanced models for disease understanding and exploring innovative therapeutic approaches, IDMIT conducts cutting-edge research to contribute to the broader scientific understanding of infectious diseases. The facility, spanning approximately 5,141m2, includes essential BSL-2 and BSL-3 containment facilities crucial for studying infectious diseases and immunity. Notably, these facilities feature a PET-CT for whole-body in vivo imaging in BSL3/BSL2 containment.

The infrastructure is equipped with state-of-the-art materials and instruments across various disciplines (molecular biology, microscopy, cellular immunology, surgery...). Furthermore, IDMIT houses immune surveillance laboratories with multiparametric technologies like Luminex for cytokines, mass cytometry (CyTOF), and flow cytometry. These extensive resources position IDMIT at the forefront of infectious disease research, fostering advancements in innovative therapies and contributing to improved healthcare through translational outcomes.